Pyridines and derivatives
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- (12)
- (1)
- (1)
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Medchemexpress LLC Corin | 1808113-09-8 | 98.2% | 428.53 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Corin is a dual inhibitor targeting histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1. It is a chemical reagent intended for research use only and not for human use.
- Inhibits the deacetylation of semisynthetic, reconstituted nucleosomes by the CoREST ternary complex.
- Demonstrates irreversible inhibition of HDAC1 activity.
- More potent and efficacious in inducing cellular H3K9 acetylation compared to MS-275.
- Non-toxic to primary human melanocytes at 1 μM concentration.
- Available in various quantities and forms including solid or 10 mM solution.
- Shipping at room temperature.
- Storage recommendations include -20°C under nitrogen for solid form and -80°C or -20°C in solvent.
- Solubility in DMSO is 100 mg/mL.
- Protocols are provided for preparing in vivo working solutions.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 2-chloro-6-benzylamino-9-methylpurine | 101622-53-1 | MFCD00467327 | 98.2% | 273.72 g·mol⁻1 | C13H12ClN5 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CDK2-IN-13 is a small-molecule inhibitor of cyclin-dependent kinase 2 (CDK2) used for research into cell cycle regulation and cancer biology. It is reported to have an IC50 of 12 μM. Chemical identifiers include CAS 101622-53-1, molecular formula C13H12ClN5, and molecular weight 273.72 g·mol⁻1. The compound is supplied in milligram quantities for laboratory research.
- CDK2 inhibition (IC50 12 μM) suitable for target validation studies.
- Supports cancer and cell cycle research applications.
- Well-characterized identity (CAS 101622-53-1; C13H12ClN5; MW 273.72).
- High reported purity for research use (98.2%).
- Available in small-mass packaging convenient for assay development.
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eMolecules 7689-03-4 | Camptothecin | Key Organics/BIONET | MFCD00081076 | 348.358 | C20H16N2O4 | 97.000 | CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O | 5mg | 564368531
Camptothecin | Key Organics/BIONET | 7689-03-4 | MFCD00081076 | 348.358 | C20H16N2O4 | 97.000 | CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O | 5mg | 564368531
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Medchemexpress LLC M199 5mg | 1051933-86-8 | 5 MG
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M199 is a small-molecule inhibitor of Toll-like receptor 3 and 9 (TLR3/TLR9) used in research to modulate innate immune signaling. It induces secretion of IL-6, IL-8, and TNFα in human peripheral blood mononuclear cells (PBMCs) and is supplied as a solid for laboratory use.
- Potent inhibitor of TLR3 and TLR9 signaling.
- Induces secretion of IL-6, IL-8, and TNFα in human PBMCs.
- Molecular formula: C17H17N3O; molecular weight: 279.34.
- Purity: 98.6% (as listed by the supplier).
- Appearance: solid, yellow to brown.
- Storage: powder at -20°C for long-term; in solvent, store at -80°C for up to 6 months.
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Medchemexpress LLC BBT 100mg | 100mg
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BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS) BBT exhibits anti-hyperglycemia activity and protects -cells from cytokine- or streptozotocin (STZ (HY-13753))-induced cell death in type 2 diabetes models BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2 channel/CaMK2 pathway[1]
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712271 SIEBOLDIN 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712272 CYNANDIONE A 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712273 COUMESTROL STANDARD 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712275 GYMNOSIDE III 25MG
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Medchemexpress LLC VAS 3947 | 869853-70-3 | 99.6% | 310.33 | 100 MG
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VAS 3947 | 869853-70-3 | 99.6% | 310.33 | 100 MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712276 SYRINGOPICROSIDE 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712278 FUCOXANTHIN STANDAR 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712284 3 4 5 5 6 7-HEXAM 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712286 MATAIRESINOL MONOGLU 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712398 ERIGESIDE I 1MG
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